Genetic embryo testing is available at Nurture Fertility. If you’d like to discuss the testing options available to you for your IVF cycle, please contact us. us.

Preimplantation Genetic Testing-Aneuploidy (PGT-A)

Chromosomal abnormality is one of the most common causes of unsuccessful pregnancy. If an embryo has too many or too few chromosomes (a condition called aneuploidy) this can have a serious effect on its chances of developing into a fetus and then a healthy baby. In many cases, embryos with the wrong number of chromosomes stop growing by themselves, and this unfortunately may result in miscarriage.
The risk of these genetic issues is no lower with IVF treatment. However, the IVF process enables us to monitor the development of multiple embryos at the same time. We can provide PGT-A alongside IVF treatment, to help us select embryos with the correct number of chromosomes which may increase the chance of a healthy pregnancy for some patients.
The type of testing we offer is Next Generation Sequencing (NGS) from embryo biopsy at the blastocyst stage.

How does PGT-A with IVF work?

The first few stages of an IVF cycle that incorporates PGT-A are no different from any other.
Any embryos that develop to the blastocyst stage will be assessed and you will be advised if they are suitable for biopsy on day 5 or day 6 of their development. A small sample of cells from the embryo is removed using a needle by an embryologist. The sample of cells is called a biopsy and we take this from the group of cells which will go on to form the placenta to reduce the risk of damage to the cells that will form the baby. The biopsy samples are placed in tubes and sent to a specialist genetics laboratory in Nottingham. The genetic testing takes approximately 4 weeks to process so your embryos are frozen until we have the results.
The test results indicate how many copies there are of each chromosome, revealing any embryos with the incorrect number of chromosomes and therefore not likely to form a healthy pregnancy. Once the results are known, a follow up appointment will be arranged to discuss the results with a doctor.

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